Impaired Vigilance in Patients with Narcolepsy Type 1: A Psychomotor Vigilance Task Study

More severe sleepiness and an increased emotional burden could underlie the arousal and vigilance deficits seen in patients with NT1. We speculate that impaired vigilance in patients with NT1 is associated with abnormal brain function caused by a resource allocation imbalance related to hypothalamic orexin neuron damage, sleep inertia may also have a slight impact on this. Future studies should delve into this topic more deeply.

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Publication Details

Journal
Nature and Science of Sleep
Published
2024-12-01
DOI
https://doi.org/10.2147/nss.s491893
Primary Topic
Sleep and Wakefulness Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Impaired Vigilance in Patients with Narcolepsy Type 1: A Psychomotor Vigilance Task Study

Feiyan Chen, Lisan Zhang, Xiao Han, Yuyan Zhou et al.
Nature and Science of Sleep
Sleep and Wakefulness Research
article

Impaired Vigilance in Patients with Narcolepsy Type 1: A Psychomotor Vigilance Task Study

Feiyan Chen, Lisan Zhang, Xiao Han, Yuyan Zhou, Zongshan Li, Jiaqin Yu
article en

Abstract

More severe sleepiness and an increased emotional burden could underlie the arousal and vigilance deficits seen in patients with NT1. We speculate that impaired vigilance in patients with NT1 is associated with abnormal brain function caused by a resource allocation imbalance related to hypothalamic orexin neuron damage, sleep inertia may also have a slight impact on this. Future studies should delve into this topic more deeply.

Nature and Science of SleepVol. Volume 16
Capital Medical University (CN), Shaoxing University (CN), Sir Run Run Shaw Hospital (CN), Zhejiang University (CN)
Sir Run Run Shaw Hospital, Zhejiang University, Shaoxing University
No poverty
Openalex Percentile: Top 76%
Sleep and Wakefulness Research
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Impaired Vigilance in Patients with Narcolepsy Type 1: A Psychomotor Vigilance Task Study — Feiyan Chen, Lisan Zhang, et al. · Nature and Science of Sleep (2024) | TGRS Research Map | TGRS