Age-Specific Prevalence and Impact of Alcohol-Related Liver Disease: A Cross-Sectional Study"

In this study, we focus in particular on the age stratification of alcoholrelated liver disease and seek to assess its prevalence, clinical characteristics, and outcomes in patients of different ages.The main purpose was to reveal age-related trends in ARLD and its related comorbidities.A cross-sectional study based on secondary analysis of medical records of patients participating in a hepatology clinic was performed.In total, five hundred fifty patients over eighteen were included in the analysis, divided into three age categories, namely early mature individuals aged 18-35 years, middle-aged men and women aged 36-55 years, and elderly patients aged 56 and older.Older age groups were associated with statistically significant increases in liver disease severity, based on the model end-stage liver disease score (p < 0.001).In particular, individuals aged 56 and older reported a mean score of 18.5 (SD 4.2), while individuals aged 36 and 55 had a mean score of 10.5.Out of the three groups, only older adults had a significant number of cases of diabetes and hypertension, and more than one-third of participants.There is an increasing need to adjust the approach to ARLD based on the age of patients.The study provides important new data on aging and alcohol use liver health, and the appropriate screening and treatment approaches for clinical use.

Publication Details

Published
2024-12-01
DOI
https://doi.org/10.48047/afjbs.6.15.2024.11772-11780
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
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article

Age-Specific Prevalence and Impact of Alcohol-Related Liver Disease: A Cross-Sectional Study"

Liver Disease Diagnosis and Treatment
article

Age-Specific Prevalence and Impact of Alcohol-Related Liver Disease: A Cross-Sectional Study"

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Abstract

In this study, we focus in particular on the age stratification of alcoholrelated liver disease and seek to assess its prevalence, clinical characteristics, and outcomes in patients of different ages.The main purpose was to reveal age-related trends in ARLD and its related comorbidities.A cross-sectional study based on secondary analysis of medical records of patients participating in a hepatology clinic was performed.In total, five hundred fifty patients over eighteen were included in the analysis, divided into three age categories, namely early mature individuals aged 18-35 years, middle-aged men and women aged 36-55 years, and elderly patients aged 56 and older.Older age groups were associated with statistically significant increases in liver disease severity, based on the model end-stage liver disease score (p < 0.001).In particular, individuals aged 56 and older reported a mean score of 18.5 (SD 4.2), while individuals aged 36 and 55 had a mean score of 10.5.Out of the three groups, only older adults had a significant number of cases of diabetes and hypertension, and more than one-third of participants.There is an increasing need to adjust the approach to ARLD based on the age of patients.The study provides important new data on aging and alcohol use liver health, and the appropriate screening and treatment approaches for clinical use.

Vol. 6(15)
Good health and well-being
Openalex Percentile: Top 66%
Liver Disease Diagnosis and Treatment
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