Functional circuits of LYL1 controlled by supraphysiological androgen in prostate cancer cells to regulate cell senescence
Three novel feed-back loops and a novel AR- BHLHE40 / LYL1 -p27kip1 axis has been identified mediating cellular senescence in PCa cells.
Authors
- Aria Baniahmad (ORCID: https://orcid.org/0000-0003-1085-9161)
- Katrin Schindler
- Mehdi Heidari Horestani
Institutions
- Jena University Hospital (DE)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1186/s12964-024-01970-7
- Citations
- 4
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Deutscher Akademischer Austauschdienst
- Deutsche Krebshilfe
- Universitätsklinikum Jena