Therapeutical Management of Babesiosis in Cross-Bred Cow at Hyderabad, Sindh

Babesiosis is a tick-transmitted disease caused by protozoans of the genus Babesia and it is characterized by haemolytic anemia and fever, with occasional hemoglobinuria and death. In the present study, a cross-bred cow aged between 4-6 years was presented to the OPD of the departmental hospital with a history of fever, anorexia, passing coffee-colored urine, reduced milk yield, depression, and reluctance to move. Examination of the blood smears confirmed the Babesia spp. in all the cows. Microscopy detection methods are still the cheapest and fastest methods used to identify Babesia parasites although their sensitivity and specificity are limited. Haematological studies revealed reduced Hb, PCV, and TEC. Serum chemistry revealed hyperglycemia, hyperbilirubinemia, BUN, AST, and hypoprotienemia. Urine was positive for haemoglobin, glucose, and bile pigments. Three cows were treated successfully with diminazene aceturate (Berenil) at 3 mg/kg body weight, together with supportive therapy. Whereas, one cow died due to severe anemia.