Viral/Non-Viral Vectors in DNA/RNA Delivery Technology

Viral and non-viral vectors for nucleic acids (DNA/RNA) therapeutics are important in development of pharmaceutical industries. Although viral vectors have shown significant impact in transfection of DNA/RNA, but numerus studies have shown that non-viral vectors are also effective for the safe and targeted delivery of DNA/RNA to exact location in the body with high percentage of efficacy, safety, and low-immunogenicity. It is also important to protect the nucleic acids from degradation and large-scale production capability at low cost. This review article discusses the potential applications of viral vectors in DNA/RNA delivery technology, while some of the applications of non-viral vectors are compared with viral vectors.