The Pathogenesis of Alzheimers Disease and Treatment

Alzheimer's disease is caused by intracellular tau-containing neurofibrillary tangles and extracellular plaques containing A, along with some genetic risk factors like mutations in APP, PSEN1, and PSEN2. This disease is currently affecting tens of millions of people worldwide. At present, there are only drugs with therapeutic effects. Other non- drug and drug therapy all come out with little effect on treating Alzheimers Disease. Recently, researchers have discovered potential progress in therapy connected with genome editing with CRISPR-associated protein 9 (Cas9), or clustered regularly interspaced short palindromic repeats. This approach has blazed a new way in AD treatment. This article will take a review of the article and propose a few discussions on this novel approach.