Right Ventricle Function Among Patients with Wellens Syndrome Versus De Winter Syndrome

Objectives: The left ventricle ischemia or infarction led to reduction of blood flow for interventricular septum and can be affect right ventricle (RV) function. The aim of this study to compare the effects of Wellens syndrome and De Winter syndrome on the right ventricular functions. Methods: Patients presents with first attach of acute coronary syndrome and confirm diagnosed of wellness syndrome or De winter syndrome included into this study. We compare echocardiographic measurements included left ventricle (LV) function, right ventricle Fractional Area Change (RVFAC) and RV tissue doppler measurements of Tricuspid annular plane systolic excursion (TAPSE) and Tricuspid S’ peak systolic velocity within first 24 hours after admission between two syndromes. Results: A total 101 patients (82 patients with Wellens syndrome and 19 patients with De winter syndrome) included this study with mean age was 57.1±9.2 years and male patients were 83 (82.2%). The echocardiographic measurement of LV ejection fraction was not significant between two syndromes (P;0.122), but right ventricle function parameters (TAPSE, Tricuspid S’ peak systolic velocity and RVFAC) were significant lower in Di winter syndrome compared with Wellens syndrome (P values 0.0083, 0.0004 and 0.027) respectively. Conclusion: Patients with Di winter syndrome compared to Wellens syndrome had significantly higher rate of right ventricle dysfunction despite the nonsignificant changes in left ventricle systolic function.