Dose prescription and reporting in stereotactic radiosurgery: A single institutional study

Stereotactic body radiotherapy and stereotactic radiosurgery are advanced radiotherapy techniques used to treat a variety of malignancies with high precision. However, there is significant variability in dose prescription and delivery, which may impact treatment consistency and efficacy. This work presents an analysis of retrospective dosimetric data collected from 300 stereotactic body radiotherapy/stereotactic radiosurgery (SBRT/SRS) clinical treatment plans. The study evaluated the dosimetric variability across different disease sites, including lung, brain, prostate, pelvis, liver, and bone, as well as among individual treatment planning strategies. Parameters analyzed included D0.1cc, D50, D95, D99, homogeneity index, and conformity index. The results showed that, despite variations in tumor types and planning approaches, a standardized protocol at our institution helped minimize dosimetric variability. These data may facilitate interinstitutional comparisons and help to enrich the SBRT/SRS data pool for treatment standardization.