Exploring the Fecal Metabolome in Infants With Cow's Milk Allergy: The Distinct Impacts of Cow's Milk Protein Tolerance Acquisition and of Synbiotic Supplementation
This study offers no clear conclusion on the impact of CM-tolerance acquisition on the fecal metabolome. However, our results show that 6 months of synbiotic supplementation successfully altered fecal metabolome and suggest induced bifidobacteria activity, which subsequently declined after 12 months of intervention.
Authors
- Harm Wopereis (ORCID: https://orcid.org/0000-0002-2103-1442)
- Pingping Zhu
- Clara Belzer (ORCID: https://orcid.org/0000-0001-6922-836X)
- Amy C. Harms (ORCID: https://orcid.org/0000-0002-2931-4295)
- Thomas Hankemeier (ORCID: https://orcid.org/0000-0001-7871-2073)
- Mariyana V. Savova (ORCID: https://orcid.org/0000-0001-6840-6056)
- Alida S. D. Kindt (ORCID: https://orcid.org/0000-0001-6551-6030)
Institutions
- Leiden University (NL)
- Netherlands Metabolomics Centre (NL)
- Danone (Netherlands) (NL)
- Wageningen University & Research (NL)
Publication Details
- Journal
- Molecular Nutrition & Food Research
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1002/mnfr.202400583
- Citations
- 4
- Primary Topic
- Food Allergy and Anaphylaxis Research
- Type
- article
- Field-Weighted Citation Impact
- 1.53
Funders
- Danone
- Universiteit Leiden
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- China Scholarship Council
- Wageningen University and Research