Single Atom Engineered Antibiotics Overcome Bacterial Resistance (Adv. Mater. 50/2024)
Multi-Drug Resistance Single atoms of manganese, tightly bonded to carboxylated nitrogen-doped graphene, exhibit potent antibacterial properties against both Gram-negative and Gram-positive bacteria. Targeting the biomolecules of the outer bacterial membrane, the new “single-atom” engineered antibiotic effectively bypasses the development of bacterial resistance and heals infected wounds in vivo, while remaining non-toxic to human cells. More details can be found in article number 2410652 by Aristides Bakandritsos, Radek Zbořil, and co-workers.
Authors
- Pavla Kučová
- David Panáček (ORCID: https://orcid.org/0009-0008-0881-0477)
- Milan Kolář (ORCID: https://orcid.org/0000-0003-4621-8868)
- En Zhao (ORCID: https://orcid.org/0000-0003-3416-2414)
- Veronika Šedajová (ORCID: https://orcid.org/0000-0002-1635-1206)
- Martin Šrejber (ORCID: https://orcid.org/0000-0001-9556-2978)
- Giorgio Zoppellaro (ORCID: https://orcid.org/0000-0003-2304-2564)
- Michal Otyepka (ORCID: https://orcid.org/0000-0002-1066-5677)
- Radek Zbořil (ORCID: https://orcid.org/0000-0002-3147-2196)
- Zupeng Chen (ORCID: https://orcid.org/0000-0002-7351-3240)
- Rostislav Langer (ORCID: https://orcid.org/0009-0000-5470-4423)
- Aleš Panáček (ORCID: https://orcid.org/0000-0001-5429-9966)
- Renata Večeřová (ORCID: https://orcid.org/0000-0002-7546-530X)
- Markéta Paloncýová (ORCID: https://orcid.org/0000-0002-6811-7761)
- Lucie Hochvaldová (ORCID: https://orcid.org/0000-0002-6817-7887)
- Zdeňěk Baďura (ORCID: https://orcid.org/0009-0002-2330-2012)
- Aristides Bakandritsos (ORCID: https://orcid.org/0000-0003-4411-9348)
- Jianrong Zeng (ORCID: https://orcid.org/0000-0003-4867-1893)
- Lukáš Zdražil (ORCID: https://orcid.org/0000-0002-5284-9845)
- Ruibin Li (ORCID: https://orcid.org/0000-0001-6471-7658)
- Zhiqiang Xiong (ORCID: https://orcid.org/0000-0002-7984-3662)
- Tomáš Malina (ORCID: https://orcid.org/0000-0001-5631-607X)
- Jan Belza (ORCID: https://orcid.org/0000-0002-3104-6007)
- Lina Li (ORCID: https://orcid.org/0000-0003-4909-9796)
Institutions
- VSB - Technical University of Ostrava (CZ)
- Nanjing Forestry University (CN)
- Chinese Academy of Sciences (CN)
- Soochow University (CN)
- Shanghai Advanced Research Institute (CN)
- Regional Centre of Advanced Technologies and Materials (CZ)
- Palacký University Olomouc (CZ)
Publication Details
- Journal
- Advanced Materials
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/adma.202470402
- Citations
- 4
- Primary Topic
- Graphene and Nanomaterials Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.74