Optimizing Postoperative Management for PKP: Combining Traditional Chinese Medicine and Modern Rehabilitation Techniques [Letter]

Osteoporotic vertebral compression fracture (OVCF) is a common disabling condition in the elderly, 1 and traditional treatments often yield limited results. 2Percutaneous kyphoplasty (PKP) has become widely used for its ability to relieve pain and restore vertebral height. 2 However, adjacent disc degeneration (ADD) following PKP has garnered attention, with potential mechanisms including thermal damage, biomechanical alterations, and disrupted nutrient pathways from bone cement. 3Reported ADD incidence ranges from 34% to 52.6%, but whether it is directly caused by PKP or a continuation of natural degeneration remains uncertain. 3Key risk factors include preoperative disc degeneration, bone cement leakage, and altered biomechanical environments. 4Current studies are limited by inadequate multivariate analyses and short follow-ups, impeding a full understanding of ADD and complicating postoperative management.We commend Song et al 5 for their valuable contributions.The retrospective study identified severely degenerated discs (Pfirrmann grade IV) and intradiscal cement leakage (ICL) as major risk factors for ADD following PKP.The study also suggested a potential link between ADD and an increased risk of adjacent segment fractures (ASF), providing valuable evidence for understanding ADD mechanisms and guiding clinical risk assessment and intervention strategies.However, certain limitations in the study merit further investigation.First, the grouping method did not fully account for differences in disc degeneration rates.Severely degenerated discs may progress slower, while mildly degenerated discs could degenerate faster due to postoperative biomechanical changes, 6,7 potentially underestimating long-term risks for the latter.Second, the study did not control for postoperative activity levels or rehabilitation measures, which can significantly affect load distribution and influence ADD and ASF development. 8Additionally, environmental and lifestyle factors like smoking, alcohol use, and diet, which impact disc health, were not considered.Lastly, the absence of temporal analysis of ASF limits differentiation between early injury and late degeneration.Future research should explore degeneration rate differences among discs with varying preoperative conditions through longitudinal follow-up on disc height loss.Finite element analysis could simulate stress distribution to elucidate degeneration mechanisms.Standardized documentation of postoperative activity and rehabilitation, including loadbearing intensity and brace use, is also essential to assess their impact on ADD.Integrating imaging and clinical data would further optimize postoperative management.Lifestyle factors, including smoking, alcohol consumption, and dietary habits, should also be included in multi-center studies to develop comprehensive multivariable models and improve the precision of risk assessments.Most importantly, combining the holistic perspective of traditional Chinese medicine (TCM) with modern rehabilitation techniques could enhance postoperative management for PKP.Utilizing TCM approaches, such as kidney-nourishing herbal treatments (eg, Eucommia, Dipsacus), alongside osteoporosis therapies, could improve metabolic function and slow disc degeneration.Spleen-strengthening and liver-soothing strategies, coupled with guided exercises like Tai Chi or Baduanjin, may optimize spinal biomechanics and

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Publication Details

Journal
Journal of Pain Research
Published
2024-12-01
DOI
https://doi.org/10.2147/jpr.s509167
Primary Topic
Spine and Intervertebral Disc Pathology
Type
article
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article

Optimizing Postoperative Management for PKP: Combining Traditional Chinese Medicine and Modern Rehabilitation Techniques [Letter]

Chen Zhou, Zhenhua Xu
Journal of Pain Research
Spine and Intervertebral Disc Pathology
article

Optimizing Postoperative Management for PKP: Combining Traditional Chinese Medicine and Modern Rehabilitation Techniques [Letter]

Chen Zhou, Zhenhua Xu
article en

Abstract

Osteoporotic vertebral compression fracture (OVCF) is a common disabling condition in the elderly, 1 and traditional treatments often yield limited results. 2Percutaneous kyphoplasty (PKP) has become widely used for its ability to relieve pain and restore vertebral height. 2 However, adjacent disc degeneration (ADD) following PKP has garnered attention, with potential mechanisms including thermal damage, biomechanical alterations, and disrupted nutrient pathways from bone cement. 3Reported ADD incidence ranges from 34% to 52.6%, but whether it is directly caused by PKP or a continuation of natural degeneration remains uncertain. 3Key risk factors include preoperative disc degeneration, bone cement leakage, and altered biomechanical environments. 4Current studies are limited by inadequate multivariate analyses and short follow-ups, impeding a full understanding of ADD and complicating postoperative management.We commend Song et al 5 for their valuable contributions.The retrospective study identified severely degenerated discs (Pfirrmann grade IV) and intradiscal cement leakage (ICL) as major risk factors for ADD following PKP.The study also suggested a potential link between ADD and an increased risk of adjacent segment fractures (ASF), providing valuable evidence for understanding ADD mechanisms and guiding clinical risk assessment and intervention strategies.However, certain limitations in the study merit further investigation.First, the grouping method did not fully account for differences in disc degeneration rates.Severely degenerated discs may progress slower, while mildly degenerated discs could degenerate faster due to postoperative biomechanical changes, 6,7 potentially underestimating long-term risks for the latter.Second, the study did not control for postoperative activity levels or rehabilitation measures, which can significantly affect load distribution and influence ADD and ASF development. 8Additionally, environmental and lifestyle factors like smoking, alcohol use, and diet, which impact disc health, were not considered.Lastly, the absence of temporal analysis of ASF limits differentiation between early injury and late degeneration.Future research should explore degeneration rate differences among discs with varying preoperative conditions through longitudinal follow-up on disc height loss.Finite element analysis could simulate stress distribution to elucidate degeneration mechanisms.Standardized documentation of postoperative activity and rehabilitation, including loadbearing intensity and brace use, is also essential to assess their impact on ADD.Integrating imaging and clinical data would further optimize postoperative management.Lifestyle factors, including smoking, alcohol consumption, and dietary habits, should also be included in multi-center studies to develop comprehensive multivariable models and improve the precision of risk assessments.Most importantly, combining the holistic perspective of traditional Chinese medicine (TCM) with modern rehabilitation techniques could enhance postoperative management for PKP.Utilizing TCM approaches, such as kidney-nourishing herbal treatments (eg, Eucommia, Dipsacus), alongside osteoporosis therapies, could improve metabolic function and slow disc degeneration.Spleen-strengthening and liver-soothing strategies, coupled with guided exercises like Tai Chi or Baduanjin, may optimize spinal biomechanics and

Journal of Pain ResearchVol. Volume 17
Guangzhou University of Chinese Medicine (CN)
Openalex Percentile: Top 63%
Spine and Intervertebral Disc Pathology
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