Framework Nucleic Acid‐Based Selective Cell Catcher for Endogenous Stem Cell Recruitment (Adv. Mater. 50/2024)

Endogenous Stem Cell Recruitment Using the precise programmability of tetrahedral framework nucleic acids (tFNA), Yunfeng Lin, Taoran Tian, and co-workers introduce a novel strategy for endogenous stem cell enrichment. This strategy employs the MSC-targeting aptamer Apt19S, optimizing its distribution and topology on tFNA to address challenges like cellular internalization and low affinity, thereby improving MSC binding and capture efficiency. This acellular, regenerative platform holds great potential for various clinical applications in tissue regeneration. More details can be found in article number 2406118.

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Publication Details

Journal
Advanced Materials
Published
2024-12-01
DOI
https://doi.org/10.1002/adma.202470400
Citations
1
Primary Topic
Advanced biosensing and bioanalysis techniques
Type
article
Field-Weighted Citation Impact
0.23
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Framework Nucleic Acid‐Based Selective Cell Catcher for Endogenous Stem Cell Recruitment (Adv. Mater. 50/2024)

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article

Framework Nucleic Acid‐Based Selective Cell Catcher for Endogenous Stem Cell Recruitment (Adv. Mater. 50/2024)

Weitong Cui, Yuting Yang, Yunfeng Lin, Ye Chen‐Izu, Wumeng Yin, Taoran Tian, Yong Li, Tao Zhang, Xingyu Chen, Zhiqiang Liu, Jiafei Sun, Wenjuan Ma, Yang Gao, Ziang Xu
article en
1 citations

Abstract

Endogenous Stem Cell Recruitment Using the precise programmability of tetrahedral framework nucleic acids (tFNA), Yunfeng Lin, Taoran Tian, and co-workers introduce a novel strategy for endogenous stem cell enrichment. This strategy employs the MSC-targeting aptamer Apt19S, optimizing its distribution and topology on tFNA to address challenges like cellular internalization and low affinity, thereby improving MSC binding and capture efficiency. This acellular, regenerative platform holds great potential for various clinical applications in tissue regeneration. More details can be found in article number 2406118.

Advanced MaterialsVol. 36(50)
Sichuan University (CN)
Zero hunger
Openalex Percentile: Top 40%
Advanced biosensing and bioanalysis techniques
0.23
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