PAD4 Inhibitor‐Loaded Layered Double Hydroxide Nanosheets as a Multifunctional Nanoplatform for Photodynamic Therapy‐Mediated Tumor Metastasis Treatment (Small 50/2024)
Tumor Metastasis Treatment PAD4 inhibitor-loaded DR-CoMo-LDH nanosheets can generate ROS under 1270 nm laser irradiation, effectively killing tumor cells and inducing immunogenic cell death. Additionally, laser irradiation facilitates the release of PAD4 inhibitor, which suppresses NETs formation, thereby exerting a synergistic PDT/immunotherapy effect. More in article number 2404211, Chaoliang Tan, Ruizheng Liang, Yuji Wang, and co-workers.
Authors
- Yuji Wang (ORCID: https://orcid.org/0000-0003-3842-7627)
- Ruizheng Liang (ORCID: https://orcid.org/0000-0002-3930-9625)
- Chaoliang Tan (ORCID: https://orcid.org/0000-0003-1695-5285)
- Shuqing Yang
- Min Zhang (ORCID: https://orcid.org/0000-0002-9169-1024)
- Rong Chen (ORCID: https://orcid.org/0000-0002-3667-4387)
- Yu Lu (ORCID: https://orcid.org/0000-0003-4151-3120)
- Tingting Hu (ORCID: https://orcid.org/0000-0001-8017-2619)
Institutions
- City University of Hong Kong (HK)
- Capital Medical University (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Quzhou University (CN)
- Beijing University of Chemical Technology (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Small
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/smll.202470373
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00