Association of intraoperative hypotension and cumulative norepinephrine dose with postoperative acute kidney injury in patients having noncardiac surgery: a retrospective cohort analysis
Both intraoperative hypotension and cumulative intraoperative norepinephrine dose were independently associated with postoperative AKI in patients undergoing noncardiac surgery. Pending results of trials testing whether these relationships are causal, it seems prudent to avoid both profound hypotension and high norepinephrine doses in adults undergoing noncardiac surgery.
Authors
- Christian Koch (ORCID: https://orcid.org/0000-0002-2655-7363)
- Moritz Flick (ORCID: https://orcid.org/0000-0003-4415-9956)
- Kerstin Rubarth (ORCID: https://orcid.org/0000-0002-6174-6346)
- Bernd Saugel (ORCID: https://orcid.org/0000-0001-6619-0722)
- Dominik Leicht (ORCID: https://orcid.org/0009-0003-3144-4165)
- Michael Sander (ORCID: https://orcid.org/0000-0003-1677-3609)
- Karim Kouz (ORCID: https://orcid.org/0000-0001-8107-6952)
- Marit Habicher (ORCID: https://orcid.org/0000-0001-8964-3819)
- Christian Hahn (ORCID: https://orcid.org/0000-0002-2758-7222)
- Felix Balzer (ORCID: https://orcid.org/0000-0003-1575-2056)
- Emmanuel Schneck (ORCID: https://orcid.org/0000-0003-0565-1550)
- Melanie Markmann (ORCID: https://orcid.org/0000-0003-0682-0301)
- Christian Katzer
Institutions
- Universität Hamburg (DE)
- Justus-Liebig-Universität Gießen (DE)
- Humboldt-Universität zu Berlin (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- British Journal of Anaesthesia
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1016/j.bja.2024.11.005
- Citations
- 41
- Primary Topic
- Cardiac, Anesthesia and Surgical Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 16.48