Safety and toxicity of Iopofosine I 131 (CLR 131) with external beam radiation therapy in recurrent or metastatic head and neck cancer: results of a phase 1 single-centre, open-label, single-arm, dose escalation and dose expansion study
National Institutes of HealthP50 DE026787, National Cancer InstituteP30 CA014520, National Institutes of Health1UL1TR002373, Cellectar, NCT04105543.
Authors
- Jarrod Longcor (ORCID: https://orcid.org/0000-0001-5890-4692)
- Nicole Rogus‐Pulia (ORCID: https://orcid.org/0000-0001-7294-4180)
- Paul M. Harari (ORCID: https://orcid.org/0000-0002-6207-5505)
- Gregory K. Hartig (ORCID: https://orcid.org/0000-0002-0302-7319)
- Shari M. Piaskowski
- Steve Y. Cho (ORCID: https://orcid.org/0000-0003-2724-7778)
- Timothy M. McCulloch (ORCID: https://orcid.org/0000-0002-4678-9161)
- Kate Oliver (ORCID: https://orcid.org/0000-0002-0595-9080)
- Justine Y. Bruce (ORCID: https://orcid.org/0000-0002-5902-7430)
- Menggang Yu (ORCID: https://orcid.org/0000-0002-7904-3155)
- Tiffany A. Glazer (ORCID: https://orcid.org/0000-0002-4223-9381)
- Randall J. Kimple (ORCID: https://orcid.org/0000-0001-8336-8000)
- David P. Adam (ORCID: https://orcid.org/0000-0002-8282-6660)
- Patrick M. Hill (ORCID: https://orcid.org/0000-0002-1208-0568)
- Bryan P. Bednarz (ORCID: https://orcid.org/0000-0002-7467-9816)
- Douglas K. Trask (ORCID: https://orcid.org/0000-0003-0550-442X)
- Aaron M. Wieland
Institutions
- University of Wisconsin–Madison (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- University of Wisconsin Health (US)
- Wisconsin Division of Public Health (US)
- Cellectar Biosciences (United States) (US)
- Institute for Medical Informatics and Biostatistics (CH)
Publication Details
- Journal
- EBioMedicine
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1016/j.ebiom.2024.105496
- Citations
- 2
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- University of Wisconsin Carbone Cancer Center
- National Institutes of Health
- Institute for Clinical and Translational Research, University of Wisconsin, Madison
- National Cancer Institute
- National Institute of Dental and Craniofacial Research
- National Center for Advancing Translational Sciences