Neuronal complexity tracks changes of epileptic activity and identifies epilepsy patients independent of interictal epileptiform discharges
An increase in EA caused by ASM reduction resulted in a loss of neuronal complexity in surface EEG recordings of patients with epilepsy, independent of IEDs. These findings suggest that neuronal complexity could serve as a potential biomarker to differentiate between epilepsy patients and those with NEEs only. This holds promise for improving the clinical evaluation of EA in epilepsy, addressing the limitations of seizure frequency and IED identification.
Authors
- Felix Rosenow (ORCID: https://orcid.org/0000-0002-3989-7471)
- Andrea Spyrantis (ORCID: https://orcid.org/0000-0002-7635-6295)
- M. Strüber (ORCID: https://orcid.org/0000-0002-3478-0848)
- Adam Strzelczyk (ORCID: https://orcid.org/0000-0001-6288-9915)
- Annika Süß
- Ricardo Kienitz (ORCID: https://orcid.org/0000-0003-2328-3413)
- Nina Merkel (ORCID: https://orcid.org/0000-0002-6815-7990)
Institutions
- Goethe University Frankfurt (DE)
- University Hospital Frankfurt (DE)
Publication Details
- Journal
- Epilepsia
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1111/epi.18218
- Citations
- 4
- Primary Topic
- EEG and Brain-Computer Interfaces
- Type
- article
- Field-Weighted Citation Impact
- 1.37