Unlocking the potential of Traditional Chinese Medicine (TCM): Shipi Xiaoji formula (SPXJF) as a novel ferroptosis inducer in hepatocellular carcinoma
SPXJF exerts anti-tumor effects on HCC cells by inducing ferroptosis, and its mechanism of action involves the regulation of ferroptosis-related genes and proteins. This study provides a theoretical basis for the clinical treatment of HCC and the development of new anti-cancer drugs, offering a valuable contribution to the field of ethnopharmacology.
Authors
- Puhua Zeng (ORCID: https://orcid.org/0000-0001-6542-673X)
- Xinying Fu
- Wei Peng (ORCID: https://orcid.org/0009-0003-7526-1360)
- Zhibing Wang (ORCID: https://orcid.org/0000-0003-3184-1884)
- Ling Wu (ORCID: https://orcid.org/0000-0002-5464-5918)
- Wenhui Gao (ORCID: https://orcid.org/0009-0003-1919-2137)
- Renyi Yang (ORCID: https://orcid.org/0000-0003-4839-6895)
- Kexiong Li
- Xiaoning Tan
- Peisen Xue
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- Hunan Academy of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1016/j.jep.2024.119236
- Citations
- 8
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.35