Quantitative Contribution of Clinical Attacks to Residual Disability in Patients With AQP4-Antibody Neuromyelitis Optica Spectrum Disorder
The quantitative contribution of relapse to the residual disability in patients with AQP4-NMOSD varies across phenotypes, and this relapse-related disability progression may also vary by the onset age. Although this retrospective single-center study may need validation in other data sets, these findings may help predict disability and provide a modeling tool for longer term disability in the cost-effective analysis of newer interventions.
Authors
- Jeremy Hobart (ORCID: https://orcid.org/0000-0002-2114-7920)
- Ruth Dobson (ORCID: https://orcid.org/0000-0002-2993-585X)
- E. O'Sullivan (ORCID: https://orcid.org/0000-0003-0099-3551)
- Yael Hacohen (ORCID: https://orcid.org/0000-0001-8490-9657)
- Susan M. Cooper (ORCID: https://orcid.org/0009-0008-1227-8540)
- Ruth Geraldes (ORCID: https://orcid.org/0000-0001-5829-808X)
- Maria Isabel Leite (ORCID: https://orcid.org/0000-0002-4277-9855)
- Sithara Ramdas (ORCID: https://orcid.org/0000-0003-3790-2190)
- Cheryl Hemingway (ORCID: https://orcid.org/0000-0002-3899-3015)
- Christopher Halfpenny (ORCID: https://orcid.org/0000-0002-0248-7751)
- Bo Chen (ORCID: https://orcid.org/0000-0002-7974-9051)
- Anna Francis
- Jacqueline A. Palace (ORCID: https://orcid.org/0000-0003-4779-6133)
- Roswell Martin
- V. Williams (ORCID: https://orcid.org/0000-0002-2819-6194)
- Waleed Rashid (ORCID: https://orcid.org/0009-0008-8239-2947)
Institutions
- University Hospitals Sussex NHS Foundation Trust (GB)
- University College London (GB)
Publication Details
- Journal
- Neurology
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1212/wnl.0000000000210137
- Citations
- 5
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.12
Funders
- Medical Research Council