Organs-on-a-chip to understand reproduction

Organs-on-a-chip technology (OoC) has transformed biomedical research with realistic human organ models for drug testing and disease research. While still in its infancy in reproductive research, OoC holds immense potential. The development and use of OoC platforms specifically for reproductive processes are highlighted here, including a multi-organ platform for studying the female reproductive tract, devices for investigating embryo implantation, and microfluidic systems aimed at improving pre-implantation embryos. These findings emphasize the transformative potential of OoC technology in reproductive biology, advocating for its broader adoption in the field. The potential applications of OoC technology in both human and animal reproduction are vast and significant. By providing detailed and controlled models of reproductive systems, OoC technology is set to transform reproductive health research, steering it towards a more sustainable and ethical future.