Predicting the likelihood of <i>BRCA1/2</i> germline pathogenic variants in unselected patients with breast cancer: analysis of more than 10,000 individuals
Our model provides a useful tool for accurately assessing the <i>BRCA1/2</i> carrier probability for unselected patients with breast cancer.
Authors
- Yuntao Xie (ORCID: https://orcid.org/0000-0003-1151-8107)
- Jiuan Chen
- Jie Sun (ORCID: https://orcid.org/0000-0002-3466-1371)
- Ye Xu (ORCID: https://orcid.org/0000-0002-5520-3839)
- Yao Lü (ORCID: https://orcid.org/0000-0002-3380-7762)
- Juan Zhang (ORCID: https://orcid.org/0000-0001-6241-7176)
- Li Hu (ORCID: https://orcid.org/0000-0002-6657-4707)
Institutions
- Peking University (CN)
- Peking University Cancer Hospital (CN)
- Ministry of Education (ET)
Publication Details
- Journal
- Journal of Medical Genetics
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1136/jmg-2024-110332
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China