Internal and external factors driving the evolution of the Bacterial Resistance Landscape

Bacterial resistance to antibiotics is a growing public health challenge, influenced by mechanisms such as the production of hydrolytic enzymes, modification of active sites and decreased permeability in bacteria. Based on a SWOT analysis, significant internal deficiencies in the training of health professionals and the lack of adequate technologies to diagnose resistance were identified, contributing to the prevalence of resistant infections. Additionally, lax policies on antibiotic use exacerbate the problem. On the other hand, there are strengths such as the presence of advanced surveillance and diagnostic systems, along with educational initiatives and laboratories dedicated to research. Opportunities include access to rapid diagnostic technologies and research funding that can accelerate the response to this crisis. However, threats such as self-medication and the use of counterfeit antibiotics persist due to distribution problems. It was concluded that it is crucial to implement strategies that enhance continuous training, promote the use of advanced diagnostic technologies, and strengthen research for the development of new treatments. The success of these strategies will depend on a combination of educational policies, technological improvements and stricter controls on the distribution of antibiotics to minimize the risks associated with bacterial resistance