Association of the Cervical Canal Area With Disability and Progression in People With Multiple Sclerosis
CCaA was associated with baseline EDSS scores and clinical worsening in a multicentric MS cohort, suggesting the existence of spinal cord reserve. PwPMS had a smaller CCaA, indicating that reduced spinal cord reserve might be characteristic of progressive MS. Therefore, spinal cord reserve may represent a novel radiologic marker for better understanding physical disability in MS.
Authors
- Neus Mongay‐Ochoa (ORCID: https://orcid.org/0000-0002-0338-4797)
- Massimo Filippi (ORCID: https://orcid.org/0000-0002-5485-0479)
- Cristina Auger (ORCID: https://orcid.org/0000-0001-9846-4767)
- Carsten Lukas (ORCID: https://orcid.org/0000-0002-8562-9697)
- Jaume Sastre‐Garriga (ORCID: https://orcid.org/0000-0002-1589-2254)
- Achim Gass (ORCID: https://orcid.org/0000-0003-0294-2555)
- Alvino Bisecco (ORCID: https://orcid.org/0000-0002-7202-4445)
- Eva M. M. Strijbis (ORCID: https://orcid.org/0000-0001-6705-5864)
- Deborah Pareto (ORCID: https://orcid.org/0000-0001-7356-3769)
- Paola Valsasina (ORCID: https://orcid.org/0000-0001-5390-2655)
- Xavier Montalbán (ORCID: https://orcid.org/0000-0002-0098-9918)
- Marios Yiannakas (ORCID: https://orcid.org/0000-0003-4986-446X)
- Floriana De Angelis (ORCID: https://orcid.org/0000-0002-9833-1435)
- Claudio Gobbi (ORCID: https://orcid.org/0000-0002-7554-0664)
- Mar Tintoré (ORCID: https://orcid.org/0000-0001-9999-5359)
- Pere Carbonell‐Mirabent (ORCID: https://orcid.org/0000-0003-1349-9261)
- Nathane Braga (ORCID: https://orcid.org/0000-0003-2942-6622)
- Monica Margoni (ORCID: https://orcid.org/0000-0002-9232-8964)
- Manel Alberich
- Philipp Eisele (ORCID: https://orcid.org/0000-0001-6831-4282)
- Ángela Vidal‐Jordana (ORCID: https://orcid.org/0000-0002-7270-5507)
- Àlex Rovira (ORCID: https://orcid.org/0000-0002-2132-6750)
- Frederik Barkhof (ORCID: https://orcid.org/0000-0003-3543-3706)
- Olga Ciccarelli (ORCID: https://orcid.org/0000-0001-7485-1367)
- Menno Michiel Schoonheim (ORCID: https://orcid.org/0000-0002-2504-6959)
- Chiara Zecca (ORCID: https://orcid.org/0000-0002-9990-3431)
- Alessandro Meani (ORCID: https://orcid.org/0000-0001-8189-0452)
- Maria Assunta Rocca (ORCID: https://orcid.org/0000-0003-2358-4320)
- Barbara Bellenberg (ORCID: https://orcid.org/0000-0001-7484-6787)
- Antonio Gallo (ORCID: https://orcid.org/0000-0002-2203-6237)
- Paolo Preziosa (ORCID: https://orcid.org/0000-0002-7826-0019)
- Jacqueline A. Palace (ORCID: https://orcid.org/0000-0003-4779-6133)
- Lisa Matthews
Institutions
- MACOM (United States) (US)
- University College London (GB)
Publication Details
- Journal
- Neurology
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1212/wnl.0000000000210136
- Citations
- 5
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.12