Myelin basic protein and TREM2 quantification in the CSF of patients with Multiple System Atrophy and other Parkinsonian conditions
In conclusion, MBP, but not TREM2, is elevated in the CSF of not only MSA but in all atypical Parkinsonian conditions compared to idiopathic Parkinson's disease. This highlights the value of the evaluation of myelin/oligodendrocyte-associated markers in neurodegenerative movement disorders.
Authors
- Kathrin Brockmann (ORCID: https://orcid.org/0000-0002-7515-8596)
- Matthias Schmitz (ORCID: https://orcid.org/0000-0002-5502-681X)
- Inga Zerr (ORCID: https://orcid.org/0000-0002-6722-2463)
- Mathias Bähr (ORCID: https://orcid.org/0000-0002-9570-1592)
- Fabian Maass (ORCID: https://orcid.org/0000-0002-4077-2852)
- Matthis Synofzik (ORCID: https://orcid.org/0000-0002-2280-7273)
- Christoph van Riesen (ORCID: https://orcid.org/0000-0003-1734-2421)
- Claudia Schulte (ORCID: https://orcid.org/0000-0003-4006-1265)
- Sezgi Canaslan (ORCID: https://orcid.org/0000-0001-5366-129X)
- Péter Hermann (ORCID: https://orcid.org/0000-0003-1889-8325)
Institutions
- German Center for Neurodegenerative Diseases (DE)
- Universitätsmedizin Göttingen (DE)
- Hertie Institute for Clinical Brain Research (DE)
- University of Göttingen (DE)
- University of Tübingen (DE)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1007/s00415-024-12747-w
- Citations
- 11
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.06