[Exploration of electroacupuncture at "Fengchi" (GB 20) and "Sishencong" (EX-HN 1) for attenuating learning and memory impairment in vascular dementia rats based on NMDAR/CREB/BDNF signaling pathway].
EA at "Fengchi" (GB 20) and "Sishencong" (EX-HN 1) can attenuate learning and memory impairment in VD rats, which may be obtained by reducing GLU level in hippocampal tissue, inhibiting hippocampal excitotoxicity, mediating protein expression related to the NMDAR/CREB/BDNF signaling pathway, and maintaining neuronal survival and growth.
Authors
- Tong Wu (ORCID: https://orcid.org/0000-0001-9968-9909)
- Hongxu Zhao
- Sun We (ORCID: https://orcid.org/0000-0001-6841-5497)
- Ruiqi Qin (ORCID: https://orcid.org/0000-0003-0102-9588)
- Junfeng Li (ORCID: https://orcid.org/0000-0003-3688-3493)
- Changqing Li (ORCID: https://orcid.org/0000-0002-1269-0964)
- Yusheng Han
- Yinghua Chen (ORCID: https://orcid.org/0000-0002-5020-7507)
- Yuanyu Song
- Xiaoqing Su
- H. Wang (ORCID: https://orcid.org/0009-0001-2467-5331)
Institutions
- First Affiliated Hospital of Heilongjiang University of Chinese Medicine (CN)
- Heilongjiang University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-12-12
- DOI
- https://doi.org/10.13703/j.0255-2930.20240605-k0003
- Citations
- 2
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article