Programmed Cell Death Protein 1 Contributes to Oral Cancer Pain via Regulating Tumor Necrosis Factor Alpha in the Spinal Trigeminal Nucleus Caudalis
Our results suggest that PD-1 in the Sp5C contributes to oral cancer pain by altering TNFα signaling in the trigeminal nociceptive system, and PD-1 could be targeted to develop a novel approach for oral cancer pain management.
Authors
- Feng Tao (ORCID: https://orcid.org/0000-0002-0623-6298)
- John C. Dolan
- Brian L. Schmidt (ORCID: https://orcid.org/0000-0002-2409-8984)
- Runyi Mao
- Sufang Liu (ORCID: https://orcid.org/0000-0003-2677-1295)
Institutions
- New York University (US)
Publication Details
- Journal
- Current Neuropharmacology
- Published
- 2024-12-12
- DOI
- https://doi.org/10.2174/1570159x23666241209160039
- Primary Topic
- Cancer, Stress, Anesthesia, and Immune Response
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health