The cellular and extracellular proteomic signature of human dopaminergic neurons carrying the LRRK2 G2019S mutation
In conclusion, we characterized the cellular and extracellular proteome of dopaminergic neurons carrying the LRRK2 G2019S mutation and proposed an experimentally based list of biomarker candidates for future studies.
Authors
- Mohamed Ali Jarboui (ORCID: https://orcid.org/0000-0002-5203-235X)
- Fatma Büşra Işık (ORCID: https://orcid.org/0009-0009-3237-3120)
- Felix von Zweydorf (ORCID: https://orcid.org/0000-0003-4732-5278)
- Felix Knab (ORCID: https://orcid.org/0000-0002-7240-5926)
- Christian Johannes Gloeckner (ORCID: https://orcid.org/0000-0001-6494-6944)
- Giambattista Guaitoli (ORCID: https://orcid.org/0000-0003-4442-3841)
- Franziska Klose
- Anto P. Rajkumar (ORCID: https://orcid.org/0000-0003-3203-6326)
- Thomas Gasser (ORCID: https://orcid.org/0000-0002-1069-1146)
Institutions
- University of Nottingham (GB)
- German Center for Neurodegenerative Diseases (DE)
- Institute of Mental Health (GB)
- Hertie Institute for Clinical Brain Research (DE)
- University of Tübingen (DE)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2024-12-12
- DOI
- https://doi.org/10.3389/fnins.2024.1502246
- Citations
- 2
- Primary Topic
- RNA regulation and disease
- Type
- article
- Field-Weighted Citation Impact
- 0.47