REPRODUCTION OF LEUKEMIC INFECTION IN THE BODY OF A GUINEA PIG

The article presents data on experimental infection of guinea pigs with bovine leukemia virus (BLVV). Animals were intraperitoneally injected with a cell suspension of lymphocytes obtained from a cow with leukemia in hematological form. It was found that in 100% of individuals, specific fluorescence of lymphocytes was detected on the 14th day after infection, and proviral DNA was detected on the 21st day. The presence of the virus was also confirmed using PCR and RNIF in all animals on the 180th day after infection.

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Published
2024-12-10
DOI
https://doi.org/10.52686/conferencearticle_67597cf011e046.80425323
Primary Topic
T-cell and Retrovirus Studies
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article
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article

REPRODUCTION OF LEUKEMIC INFECTION IN THE BODY OF A GUINEA PIG

T.S. Dudoladova, Н. Н. Новикова
T-cell and Retrovirus Studies
article

REPRODUCTION OF LEUKEMIC INFECTION IN THE BODY OF A GUINEA PIG

T.S. Dudoladova, Н. Н. Новикова
article en

Abstract

The article presents data on experimental infection of guinea pigs with bovine leukemia virus (BLVV). Animals were intraperitoneally injected with a cell suspension of lymphocytes obtained from a cow with leukemia in hematological form. It was found that in 100% of individuals, specific fluorescence of lymphocytes was detected on the 14th day after infection, and proviral DNA was detected on the 21st day. The presence of the virus was also confirmed using PCR and RNIF in all animals on the 180th day after infection.

Omsk State Institute of Service (RU)
Good health and well-being
Openalex Percentile: Top 70%
T-cell and Retrovirus Studies
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REPRODUCTION OF LEUKEMIC INFECTION IN THE BODY OF A GUINEA PIG — T.S. Dudoladova, Н. Н. Новикова · (2024) | TGRS Research Map | TGRS