BIBR1532 inhibits proliferation and metastasis of esophageal squamous cancer cells by inducing telomere dysregulation
BIBR1532 exerts anti-cancer effects on ESCC by inducing DDR through the ATR/CHK1 and ATM/CHK2 pathways and downregulating the expression of telomere-binding proteins.
Authors
- Qiang Ma (ORCID: https://orcid.org/0000-0002-6379-9927)
- Maoju Tang
- Xiaolan Guo (ORCID: https://orcid.org/0000-0003-2948-8997)
- Xiaowu Zhong (ORCID: https://orcid.org/0000-0001-5143-5838)
- Qin Wang (ORCID: https://orcid.org/0000-0001-9852-5347)
- Lei Xu (ORCID: https://orcid.org/0000-0002-9241-7019)
- Xiao Liu (ORCID: https://orcid.org/0000-0002-8073-0534)
- Qingrong Li (ORCID: https://orcid.org/0000-0003-4835-2219)
- Zichun Yuan
- Man Luo (ORCID: https://orcid.org/0009-0005-9201-4956)
Institutions
- North Sichuan Medical University (CN)
- Affiliated Hospital of North Sichuan Medical College (CN)
Publication Details
- Journal
- World Journal of Gastrointestinal Oncology
- Published
- 2024-12-11
- DOI
- https://doi.org/10.4251/wjgo.v17.i1.99376
- Citations
- 3
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 0.98