Dihydropyrimidine dehydrogenase polymorphisms in patients with gastrointestinal malignancies and their impact on fluoropyrimidine tolerability: Experience from a single Italian institution

Although this study had a limited sample size, it provides additional information on the prevalence of <i>DPYD</i> polymorphisms in the Italian population and highlights the role of pharmacogenetic testing to prevent severe toxicity.

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Publication Details

Journal
World Journal of Gastrointestinal Oncology
Published
2024-12-11
DOI
https://doi.org/10.4251/wjgo.v17.i1.96822
Citations
2
Primary Topic
Colorectal Cancer Treatments and Studies
Type
article
Field-Weighted Citation Impact
0.57
Controls
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article

Dihydropyrimidine dehydrogenase polymorphisms in patients with gastrointestinal malignancies and their impact on fluoropyrimidine tolerability: Experience from a single Italian institution

Maria D’Amato, Gennaro Iengo, Nicholas Massa, Chiara Carlomagno
2 citations
World Journal of Gastrointestinal Oncology
Colorectal Cancer Treatments and Studies
0.57
article

Dihydropyrimidine dehydrogenase polymorphisms in patients with gastrointestinal malignancies and their impact on fluoropyrimidine tolerability: Experience from a single Italian institution

Maria D’Amato, Gennaro Iengo, Nicholas Massa, Chiara Carlomagno
article en
2 citations

Abstract

Although this study had a limited sample size, it provides additional information on the prevalence of <i>DPYD</i> polymorphisms in the Italian population and highlights the role of pharmacogenetic testing to prevent severe toxicity.

World Journal of Gastrointestinal OncologyVol. 17(1)
Ospedale Santa Maria (IT), Federico II University Hospital (IT), University of Naples Federico II (IT)
Good health and well-being
Openalex Percentile: Top 26%
Colorectal Cancer Treatments and Studies
0.57
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