<scp>LRP1B</scp> Suppresses Immunotherapy Efficacy in Lung Adenocarcinoma by Preventing Ferroptosis
Our results confirmed that LRP1B affected the efficacy of immunotherapy by modulating the sensitivity of NSCLC cells to ferroptosis. LRP1B mutations represent a highly promising immunotherapeutic biomarker for NSCLC.
Authors
- Yan Xiang (ORCID: https://orcid.org/0000-0002-2258-0742)
- Ying Chen
- Zihao Ke (ORCID: https://orcid.org/0009-0004-0687-4275)
- Kaihua Lu (ORCID: https://orcid.org/0000-0003-4744-4824)
- Qi Zhang (ORCID: https://orcid.org/0000-0002-5055-3637)
- Tao Yu (ORCID: https://orcid.org/0000-0002-1000-8861)
Institutions
- Ningbo University (CN)
- Nantong University (CN)
- The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/cam4.70486
- Citations
- 4
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- National Natural Science Foundation of China