Evaluation of curcumin nanoparticles of various sizes for targeting multidrug-resistant lung cancer cells via inhalation
Nebulized Cur-NPs formulations could be internalized into the H69AR cells. The Cur-NPs toxicity toward the H69AR was size and time-dependent. Cur-NP30 nm was more effective than Cur-NP200 nm to retain within the cells to exert higher oxidative stresss-induced cell death.
Authors
- Paul M. Young (ORCID: https://orcid.org/0000-0002-4357-7999)
- Ching-Yee Loo
- Stewart Yeung (ORCID: https://orcid.org/0009-0000-2771-9988)
- Wing‐Hin Lee (ORCID: https://orcid.org/0000-0003-0212-6523)
- Daniela Traini (ORCID: https://orcid.org/0000-0002-7173-017X)
- Chean Ring Leong (ORCID: https://orcid.org/0000-0002-2692-0097)
Institutions
- University of Technology Sydney (AU)
- Woolcock Institute of Medical Research (AU)
- University of Kuala Lumpur (MY)
- Macquarie University (AU)
Publication Details
- Journal
- Nanomedicine
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1080/17435889.2024.2439241
- Citations
- 2
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.34
Funders
- University of Kuala Lumpur
- National Health and Medical Research Council