Investigating the combinatory effect of Sclerocarya birrea with doxorubicin against selected colorectal cancer cell lines
Based on the findings from the combination treatment, the SBE and SBW extracts demonstrated higher efficacy and synergistic effects combined with DOX at IC<sub>75</sub> compared to the combination of DOX and VER, suggesting their potential as anticancer agents. However, further research on both the SBE and SBW extracts' mechanisms of action and in vivo effects is warranted.
Authors
- Abhay Prakash Mishra (ORCID: https://orcid.org/0000-0002-2224-0852)
- Innocensia Mangoato (ORCID: https://orcid.org/0000-0003-1192-1887)
- Motlalepula G. Matsabisa (ORCID: https://orcid.org/0000-0003-2921-8882)
- Thembelihle Sinegugu Nxasana (ORCID: https://orcid.org/0000-0001-7114-9302)
- Patriciah Masiu (ORCID: https://orcid.org/0000-0002-8148-7548)
Institutions
- University of the Free State (ZA)
- Naresuan University (TH)
Publication Details
- Journal
- Drug Target Insights
- Published
- 2024-12-11
- DOI
- https://doi.org/10.33393/dti.2024.3219
- Citations
- 1
- Primary Topic
- Natural Antidiabetic Agents Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.36
Funders
- Universiteit van die Vrystaat