Obesity-Related Inflammation Reduces Treatment Sensitivity and Promotes Aggressiveness in Luminal Breast Cancer Modulating Oxidative Stress and Mitochondria
Taken together, our findings suggest that antioxidant and mitochondrial markers are key factors that reduce treatment sensitivity in obesity-related luminal breast cancer. The identified biomarkers may serve as valuable tools for the prognosis and development of more effective therapies in these patients.
Authors
- Pere Miquel Morla-Barcelo (ORCID: https://orcid.org/0000-0001-7443-8388)
- Mercedes Nadal‐Serrano (ORCID: https://orcid.org/0000-0002-1299-495X)
- Pilar Roca (ORCID: https://orcid.org/0000-0003-3878-5424)
- Margalida Torrens‐Mas (ORCID: https://orcid.org/0000-0002-2983-1620)
- Jorge Sastre‐Serra (ORCID: https://orcid.org/0000-0003-3405-0535)
- Lucas Melguizo-Salom (ORCID: https://orcid.org/0009-0009-8145-7531)
Institutions
- Instituto de Salud Carlos III (ES)
- Servei de Salut de les Illes Balears (ES)
- Health Research Institute of the Balearic Islands (ES)
- Research Institute of Health Sciences (ES)
- Universitat de les Illes Balears (ES)
Publication Details
- Journal
- Biomedicines
- Published
- 2024-12-11
- DOI
- https://doi.org/10.3390/biomedicines12122813
- Citations
- 3
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.98