Interferon Gamma Receptor 2 Collaborates With Circular RNA/MicroRNA to Modulate Programmed Cell Death-Ligand 1 Levels in Nasopharyngeal Carcinoma
IFNGR2 is an oncogenic factor in NPC. The circ_001377/miR-498-3p interaction drives IFNGR2 upregulation and PD-L1 overexpression, suggesting that targeting this axis could improve therapeutic outcomes.
Authors
- Guofang Guan (ORCID: https://orcid.org/0000-0003-0633-0441)
- Ye Guo (ORCID: https://orcid.org/0000-0002-1813-9815)
- Jie Bai (ORCID: https://orcid.org/0000-0001-8424-7702)
- Ying Zhao (ORCID: https://orcid.org/0000-0002-3556-3300)
- Fang Guo (ORCID: https://orcid.org/0000-0003-0581-4030)
- Yushun Wan (ORCID: https://orcid.org/0000-0003-0496-6315)
- Duo Zhang (ORCID: https://orcid.org/0000-0002-7372-6799)
- Z. Fu
Institutions
- Second Affiliated Hospital of Jilin University (CN)
Publication Details
- Journal
- World Journal of Oncology
- Published
- 2024-12-01
- DOI
- https://doi.org/10.14740/wjon1994
- Citations
- 1
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- People's Government of Jilin Province