Ultrafast synthesis of zirconium-porphyrin framework nanocrystals from alkoxide precursors
Porphyrinic metal-organic frameworks (MOFs) offer high surface areas and tunable catalytic and optoelectronic properties, making them versatile candidates for applications in phototherapy, drug delivery, photocatalysis, electronics, and energy storage. However, a key challenge for industrial integration is the rapid, cost-effective production of suitable sizes. This study introduces Zr(IV) alkoxides as metal precursors, achieving ultrafast (∼minutes) and high-yield (>90%) synthesis of three well-known Zr-based porphyrinic MOF nanocrystals: MOF-525, PCN-224, and PCN-222, each with distinct topologies. By adjusting linker-to-metal and modulator-to-metal ratios, we attain precise control over single-phase formation. Demonstrating alkoxides' potential, we synthesized nanosized PCN-224 at room temperature within seconds using a continuous multifluidic method. This advancement greatly simplifies porphyrinic MOF production, enabling broader industrial and scientific applications.
Authors
- Thomas Devic (ORCID: https://orcid.org/0000-0001-7074-6498)
- Beatriz Pelaz (ORCID: https://orcid.org/0000-0002-4626-4576)
- José Manuel Vila‐Fungueiriño (ORCID: https://orcid.org/0000-0002-1839-0495)
- Sergio Tatay (ORCID: https://orcid.org/0000-0003-0785-866X)
- Oleg Semyonov (ORCID: https://orcid.org/0000-0002-9792-2006)
- Giulia Zampini (ORCID: https://orcid.org/0000-0002-2684-1604)
- Samuel Funes‐Hernando (ORCID: https://orcid.org/0000-0003-2380-3220)
- Sonia Martínez‐Giménez (ORCID: https://orcid.org/0000-0003-2572-4921)
- Pablo del Pino (ORCID: https://orcid.org/0000-0003-1318-6839)
- Manuel Ceballos (ORCID: https://orcid.org/0000-0002-5759-2911)
- Carlos Martí‐Gastaldo (ORCID: https://orcid.org/0000-0003-3203-0047)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Universidade de Santiago de Compostela (ES)
- Parc Científic de la Universitat de València (ES)
- Institut des Matériaux Jean Rouxel (FR)
- Center for Research in Molecular Medicine and Chronic Diseases (ES)
- Nantes Université (FR)
Publication Details
- Journal
- Cell Reports Physical Science
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1016/j.xcrp.2024.102318
- Citations
- 3
- Primary Topic
- Metal-Organic Frameworks: Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.48
Funders
- European Commission
- Xunta de Galicia
- Horizon 2020 Framework Programme
- Agencia Estatal de Investigación