Intra-Individual Reproducibility of Early and Late C-Reactive Protein and Interleukin-6 in Patients with Non-Severe Ischaemic Stroke and Carotid Atherosclerosis

Our results suggest that concordance between early- and late-phase inflammatory marker risk categories is modest, and absolute levels are not highly correlated at early and late timepoints, despite associations at both times with future vascular risk. Investigators should standardise timing of phlebotomy and analysis protocols in future studies of inflammatory biomarkers.

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Publication Details

Journal
Cerebrovascular Diseases Extra
Published
2024-12-11
DOI
https://doi.org/10.1159/000540773
Citations
1
Primary Topic
Adipokines, Inflammation, and Metabolic Diseases
Type
article
Field-Weighted Citation Impact
0.39

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article

Intra-Individual Reproducibility of Early and Late C-Reactive Protein and Interleukin-6 in Patients with Non-Severe Ischaemic Stroke and Carotid Atherosclerosis

Karl McAuley, John McCabe, Sarah Gorey, Joseph Harbison et al.
1 citations
Cerebrovascular Diseases Extra
Adipokines, Inflammation, and Metabolic Diseases
0.39
article

Intra-Individual Reproducibility of Early and Late C-Reactive Protein and Interleukin-6 in Patients with Non-Severe Ischaemic Stroke and Carotid Atherosclerosis

Karl McAuley, John McCabe, Sarah Gorey, Joseph Harbison, Rosanna Inzitari, Seán Collins, Michael Marnane, David Williams, Peter J. Kelly
article en
1 citations

Abstract

Our results suggest that concordance between early- and late-phase inflammatory marker risk categories is modest, and absolute levels are not highly correlated at early and late timepoints, despite associations at both times with future vascular risk. Investigators should standardise timing of phlebotomy and analysis protocols in future studies of inflammatory biomarkers.

Cerebrovascular Diseases ExtraVol. 15(1)
University College Dublin (IE), Royal College of Surgeons in Ireland (IE), Trinity College Dublin (IE), Beaumont Hospital (IE), Botsford Hospital (US), Mater Misericordiae University Hospital (IE), St Vincent's Hospital Melbourne (AU), Saint Vincent's Catholic Medical Center (US), The Catholic University of Korea St. Vincent's Hospital (KR), Cancer Trials Ireland (IE), St. Vincent's University Hospital (IE), Beaumont Hospital, Dearborn (US), St. James's Hospital (IE), Trials Methodology Research Network (IE)
Abbott Laboratories, Irish Heart Foundation
Good health and well-being
Openalex Percentile: Top 31%
Adipokines, Inflammation, and Metabolic Diseases
0.39
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