Serum metabolome associated with novel and legacy per- and polyfluoroalkyl substances exposure and thyroid cancer risk: A multi-module integrated analysis based on machine learning
PFAS exposure is linked to a higher risk of TC, possibly through changes in fatty acid metabolism. Larger, prospective studies are needed to confirm these findings, and the role of short-chain PFAS requires more attention.
Authors
- Qin Lian (ORCID: https://orcid.org/0000-0003-2028-2706)
- Hancheng Jiang
- Xiaobo Yang (ORCID: https://orcid.org/0000-0002-5257-5100)
- Shiping Huang (ORCID: https://orcid.org/0000-0001-8115-8368)
- Fei Wang (ORCID: https://orcid.org/0000-0003-3320-677X)
- Chunxiang Li (ORCID: https://orcid.org/0000-0002-5587-4181)
- Xiangzhi Li (ORCID: https://orcid.org/0000-0001-9407-0277)
- Yu Liang (ORCID: https://orcid.org/0009-0001-6729-3763)
- Xiangtai Zeng (ORCID: https://orcid.org/0000-0003-1202-124X)
- Xiaoyu Luo (ORCID: https://orcid.org/0000-0002-9447-2716)
- Yuanxin Lin (ORCID: https://orcid.org/0009-0006-4794-537X)
- Shifeng Wen (ORCID: https://orcid.org/0009-0009-5075-6248)
Institutions
- Guangxi University (CN)
- Guangxi Medical University (CN)
- Guangxi University of Science and Technology (CN)
- Liuzhou Maternal and Child Health Hospital (CN)
- Liuzhou General Hospital (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
- Fourth Affiliated Hospital of Guangxi Medical University (CN)
- Tumor Hospital of Guangxi Medical University (CN)
Publication Details
- Journal
- Environment International
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1016/j.envint.2024.109203
- Citations
- 14
- Primary Topic
- Per- and polyfluoroalkyl substances research
- Type
- article
- Field-Weighted Citation Impact
- 3.50
Funders
- Middle-aged and Young Teachers' Basic Ability Promotion Project of Guangxi
- Guangxi Key Research and Development Program
- Specific Research Project of Guangxi for Research Bases and Talents
- Science and Technology Innovation Plan Of Shanghai Science and Technology Commission