A Lumped Parameter Model Suggests That Infusion Studies Overestimate the Cerebrospinal Fluid Outflow Resistance in Normal Pressure Hydrocephalus
The model suggests that infusion studies and draining CSF increases the CSF<sub>fr</sub> in NPH compared to earlier techniques. Allowing for an increase in the CSF<sub>fr</sub> suggests that infusion overestimates the R<sub>out</sub> by between 23 and 33%. This study indicates that further research may be required into the utility and accuracy of infusion studies and their ability to diagnose NPH.
Authors
- Alexander Robert Bateman (ORCID: https://orcid.org/0000-0001-6090-5344)
- Grant A. Bateman (ORCID: https://orcid.org/0000-0003-3095-9047)
Institutions
- John Hunter Hospital (AU)
- UNSW Sydney (AU)
- University of Newcastle Australia (AU)
Publication Details
- Journal
- Brain Sciences
- Published
- 2024-12-11
- DOI
- https://doi.org/10.3390/brainsci14121242
- Citations
- 1
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.27