Next-Generation Sequencing Analysis on Image-Guided Biopsy Samples in Early-Stage Lung Cancer: Feasibility Study and Comparison With Surgical Samples
DNA sequencing succeeded in 97.1% of biopsies of nodules 30 mm or less, whereas RNA sequencing feasibility was lower. NGS on biopsy samples is generally reliable but requires careful review.
Authors
- Claudia I. Henschke (ORCID: https://orcid.org/0000-0002-6085-5305)
- David F. Yankelevitz (ORCID: https://orcid.org/0000-0001-7364-4294)
- Rowena Yip (ORCID: https://orcid.org/0000-0002-6208-2780)
- Arel Golombeck
- Louis Gros (ORCID: https://orcid.org/0000-0001-9331-5148)
Institutions
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- JTO Clinical and Research Reports
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1016/j.jtocrr.2024.100777
- Citations
- 3
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.26