The clinical impact of conventional therapies for adults and adolescents suffering from eosinophilic esophagitis, a type 2 inflammatory chronic disease, and their economic consequences in Italy: Systematic literature review and meta-analysis
This review provides insights into efficacy, safety, and economic impact of TCSs and PPIs in managing EoE. TCSs were more effective in achieving histologic and endoscopic responses, whereas PPIs were effective in reducing symptoms. Standardized treatment guidelines are needed because of varied treatment efficacy across studies. Future research and new therapies may enhance outcomes and reduce health care costs, improving patient quality of life.
Authors
- Massimiliano Povero (ORCID: https://orcid.org/0000-0003-0666-066X)
- Alessandro Repici (ORCID: https://orcid.org/0000-0002-1621-6450)
- Gherardo Mazziotti (ORCID: https://orcid.org/0000-0001-5458-701X)
- L Castello (ORCID: https://orcid.org/0009-0008-6014-0132)
- Francesca Fanelli (ORCID: https://orcid.org/0000-0002-7620-6895)
- Giorgio Walter Canonica (ORCID: https://orcid.org/0000-0001-8467-2557)
- Lorenzo Pradelli (ORCID: https://orcid.org/0000-0002-7648-8917)
- Edoardo Vincenzo Savarino (ORCID: https://orcid.org/0000-0002-3187-2894)
- Miryana Dobreva
- Jean Pierre Saab
Institutions
- Humanitas University (IT)
- University of Padua (IT)
- Ferioli & Gianotti (Italy) (IT)
- Sanofi (Italy) (IT)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology Global
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1016/j.jacig.2024.100383
- Citations
- 2
- Primary Topic
- Eosinophilic Esophagitis
- Type
- article
- Field-Weighted Citation Impact
- 1.15