<scp>TriHex</scp> 2.0—Advancing Skin Health Science and the <scp>TriHex</scp> Technology
The addition of Octapeptide-45 to TriHex technology in the form of TriHex 2.0 is a significant advance to TriHex technology science. Both forms demonstrate ECM remodeling and positive wound healing, but supplementary benefits are evident including increased elastin and hyaluronic acid stimulation, added effects on the basement membrane, additional wound healing capacity in basal keratinocytes and anti-senescent effects in fibroblasts. This is helpful for pre-conditioning of the skin prior to procedures and post procedure related to additional ECM remodeling, wound healing advantages, senescent cell targeting and DEJ strengthening. Clinical studies to follow.
Authors
- Alan D. Widgerow (ORCID: https://orcid.org/0000-0002-5705-8073)
- Mary E. Ziegler (ORCID: https://orcid.org/0000-0002-2223-5025)
- Faiza Shafiq (ORCID: https://orcid.org/0000-0001-6211-7712)
Institutions
- University of California, Irvine (US)
- Galderma (United States) (US)
Publication Details
- Journal
- Journal of Cosmetic Dermatology
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1111/jocd.16690
- Citations
- 5
- Primary Topic
- Cell Adhesion Molecules Research
- Type
- article
- Field-Weighted Citation Impact
- 1.91
Funders
- Galderma