sTREM2 cerebrospinal fluid levels are a potential biomarker in amyotrophic lateral sclerosis and associate with UMN burden
We found that CSF sTREM2 is elevated in ALS patients and may be a novel marker, probably reflecting upper motor unit severity and prognosis.
Authors
- Dongsheng Fan (ORCID: https://orcid.org/0000-0002-3129-9821)
- Jing Yang (ORCID: https://orcid.org/0000-0002-7356-5083)
- Xiangyi Liu (ORCID: https://orcid.org/0000-0001-6822-472X)
- Lin Jiao
- Wenjing Wang (ORCID: https://orcid.org/0000-0001-5340-3813)
- Yu Fu (ORCID: https://orcid.org/0009-0009-9150-4338)
Institutions
- Peking University (CN)
- National Health and Family Planning Commission (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2024-12-10
- DOI
- https://doi.org/10.3389/fneur.2024.1515252
- Citations
- 8
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 2.95
Funders
- National Natural Science Foundation of China
- Peking University
- Peking University Third Hospital