Monocyte‐Derived Macrophages Induce Alveolar Macrophages Death via TNF‐α in Acute Lung Injury
Our study demonstrates that MDMs contribute to AMs death during ALI through TNF-α. Targeting TNF-α may offer a therapeutic strategy to mitigate AMs death and lung injury in ALI/ARDS.
Authors
- Ruixuan Wang (ORCID: https://orcid.org/0000-0002-8040-1327)
- Junjie Xiao (ORCID: https://orcid.org/0009-0001-0418-8448)
- Fei Hou (ORCID: https://orcid.org/0000-0003-1928-072X)
- Lixin Xie (ORCID: https://orcid.org/0000-0002-1091-2041)
- Huan Wang (ORCID: https://orcid.org/0009-0008-6673-3721)
- Xiayan Wu
- Ying Liu (ORCID: https://orcid.org/0000-0002-2192-657X)
Institutions
- Chinese PLA General Hospital (CN)
- Changchun 208 Hospital (CN)
- Beijing Proteome Research Center (CN)
- PLA Academy of Military Science (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/iid3.70081
- Citations
- 8
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.92
Funders
- National Science Foundation
- National Natural Science Foundation of China