Bmi‐1 Epigenetically Orchestrates Osteogenic and Adipogenic Differentiation of Bone Marrow Mesenchymal Stem Cells to Delay Bone Aging (Adv. Sci. 46/2024)
Bone Marrow MesenchyMal steM cellsJianliang Jin, Yuli Wang, and co-workers discovered Bmi-1 epigenetically modulates osteogenic and adipogenic differentiation of bone-marrow mesenchymal stem cells (BMSCs), crucial for senile osteoporosis prevention.The image creatively depicts BMSCs as workers with "Bmi-1" helmets forming bone, with flags signifying osteoblast differentiation.
Authors
- Dong Qiu (ORCID: https://orcid.org/0000-0003-4978-2077)
- Jianliang Jin (ORCID: https://orcid.org/0000-0003-3312-3210)
- Haiyun Chen (ORCID: https://orcid.org/0000-0002-8626-1695)
- Jingyu Zhao (ORCID: https://orcid.org/0000-0001-5744-3097)
- Dengshun Miao (ORCID: https://orcid.org/0000-0002-2682-3502)
- Hua Yuan (ORCID: https://orcid.org/0000-0002-5855-2196)
- Rong Wang (ORCID: https://orcid.org/0000-0002-9947-4307)
- Ao Chen (ORCID: https://orcid.org/0000-0002-8292-7314)
- Yongjie Zhang (ORCID: https://orcid.org/0000-0002-8674-4566)
- Jiyu Li (ORCID: https://orcid.org/0000-0003-2560-1016)
- Yuli Wang (ORCID: https://orcid.org/0000-0002-5500-3351)
- Yue Wang (ORCID: https://orcid.org/0000-0002-0564-3019)
- Yifei Du (ORCID: https://orcid.org/0000-0002-2262-5808)
- Tianxiao Wang (ORCID: https://orcid.org/0009-0004-0242-2861)
- Jinge Zhang (ORCID: https://orcid.org/0009-0000-2914-8189)
- Jiawen Zhou
- Yujie Lin
Publication Details
- Journal
- Advanced Science
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/advs.202470284
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00