Reninoma: an unusual cause of growth failure
This case adds to the limited literature on paediatric reninoma. It highlights a rare presentation of reninoma causing hypertension and growth failure in a child. The growth failure was likely due to hypokalemic alkalosis-induced low insulin-like growth factor 1 (IGF-1) levels, a mechanism not previously documented in paediatric reninoma cases. Surgical excision of the tumor led to normalization of blood pressure and metabolic alkalosis with significant growth recovery.
Authors
- Mohammad Shafi Kuchay (ORCID: https://orcid.org/0000-0003-3933-6137)
- Ganesh Jevalikar (ORCID: https://orcid.org/0000-0003-0304-5880)
- Lipika Lipi (ORCID: https://orcid.org/0000-0002-2638-3519)
- Nupoor Vaghasia (ORCID: https://orcid.org/0000-0001-9540-1613)
- Ambrish Mithal
Institutions
- Medanta The Medicity (IN)
- Max Super Speciality Hospital (IN)
Publication Details
- Journal
- Journal of Pediatric Endocrinology and Metabolism
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1515/jpem-2024-0380
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 0.00