Epiretinal Membrane: Correlations Among Clinical, Immunohistochemical, and Biochemical Features and Their Prognostic Implications
Early-stage ERM is associated with better visual prognosis, fewer inner and outer retinal changes in OCT, and fewer epithelial-mesenchymal transition-related alterations in ERM tissues. Key prognostic indicators for postoperative BCVA include preoperative BCVA, IRII, EZD, myofibroblasts, and RPE cells. TGF-β1 promotes the transdifferentiation of intraocular cells, impacting OCT features directly and visual outcomes indirectly.
Authors
- Donghoon Koo (ORCID: https://orcid.org/0000-0002-3061-6880)
- Youngseop Lee (ORCID: https://orcid.org/0009-0006-7250-9203)
- Jeongmin Kim (ORCID: https://orcid.org/0000-0002-0468-8012)
- Jaiyoung Ryu (ORCID: https://orcid.org/0000-0001-7846-4700)
- Hyun Seung Yang (ORCID: https://orcid.org/0000-0002-0470-676X)
- Chan Hong Min
- Minji Kim (ORCID: https://orcid.org/0009-0002-6027-3556)
- Soojin Kim (ORCID: https://orcid.org/0009-0008-4092-8942)
- S. S. Choi (ORCID: https://orcid.org/0000-0003-1644-3407)
- Dongwoo Kim (ORCID: https://orcid.org/0009-0000-6141-060X)
Institutions
- Seoul National University (KR)
- Korea University (KR)
- Veterans Health Service Medical Center (KR)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1167/iovs.65.14.25
- Citations
- 5
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.69
Funders
- National Research Foundation
- National Research Foundation of Korea