Complement Activation Profiles Predict Clinical Outcomes in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease
Our results suggest that serum and CSF levels of CFs have diagnostic and prognostic value respectively in patients with MOGAD. These findings support the use of complement inhibitors as a therapeutic approach in these patients.
Authors
- Ana Quiroga‐Varela (ORCID: https://orcid.org/0000-0003-1989-7113)
- Sara Llufriú (ORCID: https://orcid.org/0000-0003-4273-9121)
- Victòria Fernández (ORCID: https://orcid.org/0000-0002-4809-8196)
- Andreu Vilaseca (ORCID: https://orcid.org/0000-0001-8147-8505)
- Mireia Castillo (ORCID: https://orcid.org/0000-0001-8979-3219)
- Jan D. Lünemann (ORCID: https://orcid.org/0000-0002-3007-708X)
- Álvaro Cobo‐Calvo (ORCID: https://orcid.org/0000-0002-2574-0721)
- Xavier Montalbán (ORCID: https://orcid.org/0000-0002-0098-9918)
- Luca Bollo (ORCID: https://orcid.org/0000-0002-3673-2030)
- María Sepúlveda (ORCID: https://orcid.org/0000-0002-3078-645X)
- Mar Tintoré (ORCID: https://orcid.org/0000-0001-9999-5359)
- Gary Álvarez Bravo (ORCID: https://orcid.org/0000-0003-0342-0177)
- Alessandro Dinoto (ORCID: https://orcid.org/0000-0002-3249-4792)
- Adrián Valls Carbó (ORCID: https://orcid.org/0000-0002-4831-1276)
- Javier Villacieros‐Álvarez (ORCID: https://orcid.org/0000-0002-5443-1434)
- Georgina Arrambide (ORCID: https://orcid.org/0000-0002-2657-5510)
- Sara Mariotto (ORCID: https://orcid.org/0000-0002-7806-3103)
- Carmen Espejo (ORCID: https://orcid.org/0000-0001-9949-5901)
- Thaís Armangué (ORCID: https://orcid.org/0000-0001-6192-6171)
- Lluís Ramió‐Torrentà (ORCID: https://orcid.org/0000-0002-6999-1004)
- Manuel Comabella (ORCID: https://orcid.org/0000-0002-2373-6657)
- Yolanda Blanco (ORCID: https://orcid.org/0000-0002-1834-0498)
Institutions
- Vall d'Hebron Hospital Universitari (ES)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1212/nxi.0000000000200340
- Citations
- 7
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.97