A bioinspired design approach for biomechanically matched tracheal stents

Medical implants with customizable design capabilities are an important direction for high-end medical devices. An important standard in implant design is to match the mechanical properties of the implantation site. Inspired by the ‘cartilage ring-connective tissue’ structure of natural tracheal, we propose a design approach of tracheal stent composed of ‘skeleton + filling matrix’. By establishing a mapping model of structural parameters and J-type response mechanical properties, we realize a larger degree of freedom in adjusting the J-type mechanical properties. This design approach uniquely aligns the mechanical properties of the tracheal stent with those of the native trachea. We provided a thermal field-assisted rotary printing method enabling the integration of both thermoplastic and thermoset materials, which have successfully fabricated this heterogeneous structural stent as a single piece using. Our design methodology is a great inspiration for the development of medical luminal implants with designable and adjustable mechanical properties.

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Publication Details

Journal
Virtual and Physical Prototyping
Published
2024-12-11
DOI
https://doi.org/10.1080/17452759.2024.2437510
Citations
5
Primary Topic
Tracheal and airway disorders
Type
article
Field-Weighted Citation Impact
2.09

Funders

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article

A bioinspired design approach for biomechanically matched tracheal stents

Xinhua Yao, Shuaixin Feng, Congcong Luan, Yong He et al.
5 citations
Virtual and Physical Prototyping
Tracheal and airway disorders
2.09
article

A bioinspired design approach for biomechanically matched tracheal stents

Xinhua Yao, Shuaixin Feng, Congcong Luan, Yong He, Jian Ye, Jianzhong Fu, Honghui He, Lu Tian, Yuhan Jiang, Ning Zhan
article en
5 citations

Abstract

Medical implants with customizable design capabilities are an important direction for high-end medical devices. An important standard in implant design is to match the mechanical properties of the implantation site. Inspired by the ‘cartilage ring-connective tissue’ structure of natural tracheal, we propose a design approach of tracheal stent composed of ‘skeleton + filling matrix’. By establishing a mapping model of structural parameters and J-type response mechanical properties, we realize a larger degree of freedom in adjusting the J-type mechanical properties. This design approach uniquely aligns the mechanical properties of the tracheal stent with those of the native trachea. We provided a thermal field-assisted rotary printing method enabling the integration of both thermoplastic and thermoset materials, which have successfully fabricated this heterogeneous structural stent as a single piece using. Our design methodology is a great inspiration for the development of medical luminal implants with designable and adjustable mechanical properties.

Virtual and Physical PrototypingVol. 19(1)
Zhejiang Hospital (CN), Stomatology Hospital (CN), Zhejiang University (CN)
National Natural Science Foundation of China, Zhejiang Province Public Welfare Technology Application Research Project
Openalex Percentile: Top 12%
Tracheal and airway disorders
2.09
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