A bioinspired design approach for biomechanically matched tracheal stents
Medical implants with customizable design capabilities are an important direction for high-end medical devices. An important standard in implant design is to match the mechanical properties of the implantation site. Inspired by the ‘cartilage ring-connective tissue’ structure of natural tracheal, we propose a design approach of tracheal stent composed of ‘skeleton + filling matrix’. By establishing a mapping model of structural parameters and J-type response mechanical properties, we realize a larger degree of freedom in adjusting the J-type mechanical properties. This design approach uniquely aligns the mechanical properties of the tracheal stent with those of the native trachea. We provided a thermal field-assisted rotary printing method enabling the integration of both thermoplastic and thermoset materials, which have successfully fabricated this heterogeneous structural stent as a single piece using. Our design methodology is a great inspiration for the development of medical luminal implants with designable and adjustable mechanical properties.
Authors
- Xinhua Yao (ORCID: https://orcid.org/0000-0003-0261-3938)
- Shuaixin Feng (ORCID: https://orcid.org/0000-0002-3147-6568)
- Congcong Luan (ORCID: https://orcid.org/0000-0001-6289-9400)
- Yong He (ORCID: https://orcid.org/0000-0002-9099-0831)
- Jian Ye (ORCID: https://orcid.org/0000-0003-2661-760X)
- Jianzhong Fu (ORCID: https://orcid.org/0000-0002-5289-9295)
- Honghui He
- Lu Tian (ORCID: https://orcid.org/0000-0001-9877-3041)
- Yuhan Jiang (ORCID: https://orcid.org/0000-0002-5224-6294)
- Ning Zhan
Institutions
- Zhejiang Hospital (CN)
- Stomatology Hospital (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Virtual and Physical Prototyping
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1080/17452759.2024.2437510
- Citations
- 5
- Primary Topic
- Tracheal and airway disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- National Natural Science Foundation of China
- Zhejiang Province Public Welfare Technology Application Research Project