Bedaquiline Monotherapy for Multibacillary Leprosy
In patients with multibacillary leprosy, bedaquiline monotherapy cleared <i>M. leprae</i> by 4 weeks of treatment and led to improvement in the appearance of skin lesions by 7 weeks. (Funded by Janssen Research and Development; ClinicalTrials.gov number, NCT03384641.).
Authors
- Dawn Millington
- Zuleima Aguilar
- Stephanie Young (ORCID: https://orcid.org/0009-0007-9159-0470)
- Richard W. Truman (ORCID: https://orcid.org/0000-0002-9163-7677)
- Paula Frassinetti Bessa Rebello
- Patrícia Sammarco Rosa (ORCID: https://orcid.org/0000-0002-2745-2854)
- Nyasha Bakare
- James A. Palmer (ORCID: https://orcid.org/0000-0003-0656-9110)
- Étienne Ernault
- Bart Remmerie (ORCID: https://orcid.org/0000-0003-1775-4194)
- Nacer Lounis
- Linda B. Adams (ORCID: https://orcid.org/0000-0001-6265-3531)
- Jaison Antônio Barreto
- Sandra R. Chaplan
- Ruxandra Draghia Akli
- Sarah Kulke
- Miao Wang (ORCID: https://orcid.org/0000-0003-0802-996X)
Institutions
- Instituto Lauro de Souza Lima (BR)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1056/nejmoa2312928
- Citations
- 9
- Primary Topic
- Leprosy Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.50
Funders
- Janssen Research and Development