Upregulation of PD-L1 contributes to improving the apoptosis of granulosa cells via the PI3K/AKT pathway in PCOS
PD-L1 may reduce the apoptosis of GCs through PI3K/AKT signaling pathway activation, providing a novel strategy for inhibiting the apoptosis of GCs in PCOS.
Authors
- Yuejie Zhu (ORCID: https://orcid.org/0000-0002-6088-8991)
- Jianbing Ding (ORCID: https://orcid.org/0000-0001-5506-7665)
- Yan Xia (ORCID: https://orcid.org/0000-0002-3448-4977)
- Rui Han (ORCID: https://orcid.org/0000-0003-4782-3998)
- Xiaolin La (ORCID: https://orcid.org/0000-0002-9793-2853)
- Xiaoran Liu
- E. Ye
- X.-N. Zhang
Institutions
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
- Maternal and Child Health Hospital of Xinjiang Uygur Autonomous Region (CN)
Publication Details
- Journal
- Journal of Assisted Reproduction and Genetics
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1007/s10815-024-03327-y
- Citations
- 4
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.15
Funders
- Natural Science Foundation of Xinjiang Province
- Xinjiang Medical University
- Natural Science Foundation of Xinjiang